Dress right! The American Institute of Men's and Boys' Wear ran ads in 1957 seeking to increase men's clothing sales using outright shame and scare tactics.
This has to be the most pharmaceutical advertisement of all time (and it has some strong competition). "Lady, your anxiety is showing (over a coexisting depression)" folder cover for "The Nervous System anatomical illustrations" published by Merck, Sharp and Dohme, West Point, PA. Circa. 1969. Advertises Triavil "a broad-spectrum psychotheraputic agent for the management of outpatients and hospitalized patients with psychoses or neurosis characterized by mixtures of anxiety or agitation with symptoms of depression..."